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Öğe Eosinophilic infiltration in gallbladder pathologies: A clinical dilemma(2025) Martlı, Hüseyin F.; Aydın, Arzu H.; Şahingöz, Eda; Er, Sadettin; Akgül, Özgür; Turhan, Nesrin; Tez, MesutObjectives: To determine the clinicopathological features and prevalence of Eosinophilic cholecystitis (EC) with a single-center experience. Eosinophilic cholecystitis is an exceedingly uncommon pathologic issue caused by examining cholecystectomy specimens. Methods: A retrospective analysis was performed on 8,342 cholecystectomy specimens. Of these, 33 pathology results confirmed EC and were re-examined by pathologists. This study obtained demographic data, medical histories, comorbidities, clinical laboratory results, radiological findings, and pathological information from an electronic record system. Results: The average age of the patients was 47 years, with a range of 24 to 82 years. Acute cholecystitis was reported in 5 (15.6%), chronic cholecystitis in 25 (75.8%), and cholelithiasis in 3 (9.1%) gallbladder specimens. Five of the 33 patients had liver hydatid cysts. There was no statistically significant difference in parameters such as blood eosinophil count, eosinophil ratio, eosinophil count in the gallbladder wall, and gallbladder wall thickness between patients with and without liver hydatid cysts who had eosinophilic cholecystitis. Conclusion: Eosinophilic infiltration is a component of inflammatory processes, including acute and chronic inflammation. Importantly, hydatid cysts can be observed in the liver, which relates to EC. In our study, no distinct clinical, laboratory, or radiological findings of EC were identified, and the diagnosis of EC was made pathologically.Öğe Evaluation of the necessity of simultaneous cholecystectomy in patients undergoing liver hydatid cyst surgery(Elsevier B.V., 2025) Martlı, Hüseyin Fahri; Aydın, Arzu Hazal; Şahingöz, Eda; Duru, Derviş; Er, Sadettin; Turhan, Nesrin; Tez, MesutLiver hydatid cysts remain a significant public health issue in Turkey, the Middle East, East Asia, and Russia. Surgical treatments are often employed for certain stages of this disease. However, the necessity of simultaneous cholecystectomy during these procedures remains unclear. Treating symptoms related to subsequent cholelithiasis can become more challenging. This study investigates the necessity of simultaneous cholecystectomy by following patients who underwent hydatid cyst surgery with or without concurrent cholecystectomy. Materials and methods: Patients who underwent surgery for hydatid cysts between 2019 and 2024 at the General Surgery Clinic of Ankara Bilkent City Hospital were retrospectively reviewed. A total of 97 patients were included, with 56 (54.32 %) undergoing cholecystectomy along with hydatid cyst surgery (Group 1) and 41 (45.68 %) not undergoing cholecystectomy (Group 2). Preoperative clinical, laboratory, and radiological findings, as well as intraoperative data, morbidity, mortality, and postoperative symptoms, were analyzed. Results: Patients in Group 1 had longer hospital stays, higher blood loss, and significantly higher Clavien-Dindo complication scores. In the postoperative follow-up of Group 2, 8 patients (19.51 %) developed stones or sludge, and 1 patient (2.4 %) developed polyps. Four patients (9.75 %) presented to the emergency department with cholecystitis symptoms. A total of 5 patients (12.19 %), including 4 with symptomatic cholelithiasis (9.7 %) and 1 with gallbladder polyps (2.4 %), underwent elective cholecystectomy. Two (40 %) of these cholecystectomies were performed laparoscopically, while three (60 %) were converted to open cholecystectomy. Conclusion: Simultaneous cholecystectomy during liver hydatid cyst surgery may prevent difficulties associated with treating symptoms related to subsequent cholelithiasis.Öğe Factors predicting incidentally found appendiceal tumors following appendectomy: propensity score matching analysis(Sage Public Inc, 2025) Er, Sadettin; Göktaş, Abidin; Özden, Sabri; Akın, Merve; Akın, Mercan; Martlı, Hüseyin Fahri; Aydın, Arzu Hazal; Birben, Birkan; Acehan, FatihPurpose The factors that predict coincidental appendiceal neoplasms in patients who underwent appendectomy due to appendicitis were investigated.Methods 5829 patients diagnosed with appendicitis and underwent appendectomy in the department of surgery were examined. Among these patients, patients with appendiceal neoplasia and benign pathology were selected by propensity score matching analysis in a ratio of 1:4. As a result of analysis, 74 and 274 patients were grouped as appendiceal neoplasia and benign pathology, respectively.Results The mean age of the 348 appendiceal neoplasia and benign pathology groups included in the study was 45.6 and 46.4, respectively. Appendiceal diameter, contrast enhancement in the appendix wall, and neutrophil count were independent parameters for appendiceal neoplasia pathology. The AUC value of the combination of appendix diameter, lack of enhancement in the appendix wall, and neutrophil count in distinguishing appendiceal neoplasia pathology was 0.787.Conclusion Appendix diameter, lack of wall enhancement, and neutrophil count are the three predictive indicators useful in helping clinicians suspect appendiceal neoplasms.