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    Antibacterial agent loaded fungal polymer for use as a wound dressing
    (Hacettepe Üniversitesi, 2011) Güven, Eylem; Şam, Mesut; Erdal, Ebru; Karahaliloğlu, Zeynep; Candan, Dilek; Sağlam, Necdet; Denkbaş, Emir Baki
    This study is mainly concerned with the preparation and characterization of a novel wound dressing, in the form of three-dimensional micro-porous structure, from extracellular polysaccharide produced by Trametes Versicolor, a white-rot basidiomycete. A model antibiotic (i.e., ciprofloxacin) was loaded into these wound dressings in the preparation procedure. The prepared wound dressings were investigated and evaluated in four main sections. In the first part, morphological evaluations were made by using scanning electron microscopy and the obtained images revealed that the wound dressings were having highly porous structure with interconnected pores. Antibacterial agent loaded-wound dressings were also investigated with swelling behavior, in vitro drug release and biodegradation studies. Obtained results showed that wound dressings from fungal polymer including antibacterial agent could provide great potential in the treatment of dermal wounds as a new kind of wound dressing material.