Browsing Makale Koleksiyonu by Type "article"
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(1 → 3)-β-d-glucan enhances the toxicity induced by Bortezomib in rat testis
(Blackwell Publishing Ltd, 2020)We aimed to determine the possible effects of the antioxidant agent (1 → 3)-β-D-glucan on bortezomib-induced rat testis damage. We used five groups of rats; control, (1 → 3)-β-D-glucan (75 mg/kg), bortezomib group, bortezomib ... -
18-52 yaş kadın dış genital ölçümlerinin yaş, boy, ağırlık, VKİ ve parite ile ilişkisi
(Süleyman Demirel Üniversitesi, 2024)Kadın erişkinlerde cerrahi tasarımlar ve genital estetik ameliyatlarda dış genital organların doğru ve kapsamlı ölçümleri estetik değerlendirme açısından büyük önem taşımaktadır. Bu çalışmanın amacı, estetik cerrahi için ... -
Abamektin kaynaklı mide toksisitesinde hesperidinin oksidatif stres, inflamasyon ve apoptoz üzerindeki koruyucu etkisi
(Ayşe SURUÇ, 2024)Abamektin günümüzde tarım endüstrisinde çok fazla kullanılan bir pestisit türü olup uzun süreli maruziyet sonucunda toksik etkilere sahiptir. Uzun süreli abamektin maruziyeti sonucunda özellikle oksidatif stres ilişkili ... -
Acacetin ameliorates acetylsalicylic acid-induced gastric ulcer in rats by interfering with oxidative stress, inflammation, and apoptosis
(Ali Cangül, 2023)Gastric ulcer (GU) is a benign lesion in which excessive acid and pepsin activity affects the mucosal ep- ithelium and is common worldwide. Gastrointestinal disturbances come to the fore among the side effects observed in ... -
Adverse effects of oxytetracycline and enrofloxacin on the fertility of Saanen bucks
(Springer Science and Business Media B.V., 2021)This study aimed to determine the adverse effects of oxytetracycline and enrofloxacin application on the fertility of Saanen bucks. For this purpose, twenty-four bucks were divided into three groups. Group I (control group) ... -
Aksaray Üniversitesi Eğitim ve Araştırma Hastanesi’nde 2016-2020 yılları arasında saptanan bağırsak parazitlerinin dağılımı
(Aksaray Üniversitesi, 2021)Amaç: Çalışmada Aksaray Üniversitesi Eğitim ve Araştırma Hastanesi Mikrobiyoloji-Parazitoloji Laboratuvarı’na 2015-2020 yılları arasında başvuran kişilerde bağırsak parazit enfeksiyonlarının yıllara göre dağılımını ... -
Akut Miyokart İnfarktüsünde Nötrofil/Lenfosit oranı, İmmünoglobulin M (IgM) ve İmmünoglobulin G (IgG) seviyelerinin değerlendirilmesi
(Aksaray Üniversitesi, 2022)Akut miyokard infarktüsü (AMI) vakalarında yapılan bazı rutin hematolojik parametrelerin öneminin yanı sıra immünoglobulin düzeyleriyle ilgili farklı sonuçlar bulunmaktadır. Bu çalışmada; AMI hastalarının total immunoglobulin ... -
The ameliorative effect of carvacrol on sodium arsenite-induced hepatotoxicity in rats: Possible role of Nrf2/HO-1, RAGE/NLRP3, Bax/Bcl-2/Caspase-3, and Beclin-1 pathways
(John Wiley and Sons Inc, 2024)Arsenic is a toxic environmental pollutant heavy metal, and one of its critical target tissues in the body is the liver. Carvacrol is a natural phytocompound that stands out with its antioxidant, anti-inflammatory, and ... -
The ameliorative effects of chrysin on bortezomib-induced nephrotoxicity in rats: Reduces oxidative stress, endoplasmic reticulum stress, inflammation damage, apoptotic and autophagic death
(Elsevier Ltd, 2024)Bortezomib is a proteasome inhibitor antineoplastic agent that was the first to be approved for cancer treatment. One of bortezomib's most prominent dose-limiting effects is nephrotoxicity; the underlying mechanism is ... -
Ameliorative effects of sinapic acid against vancomycin-induced testicular oxidative damage, apoptosis, inflammation, testicular histopathologic disorders and decreased epididymal sperm quality
(Elsevier, 2024)In this study, it was aimed to determine the effect of sinapic acid (SNP), a polyphenol with antioxidant, anti-inflammatory and antibacterial properties, on testicular damage caused by vancomycin (VCM), a widely used ... -
Analysis of ganglion cell complex and retinal nerve fiber layer thicknesses in turkish population
(Necmettin Erbakan Üniversitesi, 2021)To determine the effects of age and sex on retinal ganglion cell complex thickness and retinal nerve fiber layer thickness in the eyes of healthy individuals. Patients and Methods: We evaluated 393 healthy subjects aged ... -
The antagonistic effects of temozolomide and trichostatin a combination on MGMT and DNA mismatch repair pathways in Glioblastoma
(Springer, 2023)Glioblastoma is the most aggressive and fatal form of brain cancer. Despite new advancements in treatment, the desired outcomes have not been achieved. Temozolomide (TMZ) is the first-choice treatment for the last two ... -
Anti-oxidant, Anti-inflammatory, and Anti-apoptotic Effects of Rutin in Spleen Toxicity Induced by Sodium Valproate in Rats
(Bingöl Üniversitesi Fen Bilimleri Enstitüsü, 2023)Long-term exposure to sodium valproate, an anti-epileptic drug, causes toxic effects in tissues, especially by increasing oxidative stress and inflammation. Rutin is a flavanoid with anti- oxidant, anti-inflammatory and ... -
The antinociceptive effect of Adalimumab, a TNF-Alpha Inhibitor, in a Mice model of inflammatory pain
(2022)The aim of this study, evaluate the nociceptive effect of adalimumab, a TNF-alpha inhibitor, on formalin-induced inflammatory pain in mice. The antinociceptive activity of adalimumab was determined on adult male BALB-C ... -
Association of insulin-like growth factor binding protein-7 promoter methylation with esophageal cancer in peripheral blood
(Springer Science and Business Media B.V., 2022)The insulin-like growth factor (IGF) signaling pathway has an important role in many cancers, including esophageal cancer (EC). IGF-binding protein 7 (IGFBP7) is one of the proteins in this signaling pathway, and its role ... -
Beneficial effects of Chrysin on Cadmium-induced nephrotoxicity in rats: Modulating the levels of Nrf2/HO-1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling pathways
(Elsevier B.V., 2023)Cadmium (Cd) is a toxic heavy metal that targets the kidney directly in the body. Chrysin (CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and anti-apoptotic. The current study ... -
Carvacrol reduces abnormal and dead sperm counts by attenuating sodium arsenite-induced oxidative stress, inflammation, apoptosis, and autophagy in the testicular tissues of rats
(Wiley, 2023)Arsenic (As) is a highly toxic metalloid. Carvacrol (CAR) is the active ingredient of Lamiaceae plants and has various biological and pharmacological properties. The present study investigated the protective effects of ... -
Carvacrol Reduces Mercuric Chloride-Induced Testicular Toxicity by Regulating Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Histopathological Changes
(Springer, 2024)Mercuric chloride (HgCl2) is a heavy metal that is toxic to the human body. Carvacrol (CAR) is a flavonoid found naturally in plants and has many biological and pharmacological activities including anti-inflammatory, ... -
Chemopreventive effects of hesperidin against paclitaxel-induced hepatotoxicity and nephrotoxicity via amendment of Nrf2/HO-1 and caspase-3/Bax/Bcl-2 signaling pathways
(Elsevier Ireland Ltd, 2022)Paclitaxel (PTX) is a widely used chemotherapeutic drug particularly effective against lung, breast, and ovarian cancer, though its usefulness is limited due to its multi-organ toxicity. The mechanisms underlying PTX ... -
Chronic prostatitis developing due to candida infection: A case diagnosed 20 years later and review of up-to-date literature
(Elsevier, 2018)Chronic prostatitis is a disease which adversely affects the quality of life of patients and does not respond adequately to treatments. In this case, we will present an immunocompetent patient who had chronic prostatitis ...
