Yaşar, ErdoğanAktaş, HalilGül, MuratGürlevik, Uğur2024-08-022024-08-0220242667-663Xhttps:/dx.doi.org/10.4328/ACAM.22116https://hdl.handle.net/20.500.12451/12304To evaluate the effect of concomitant heart failure on diabetic retinopathy (DR) in patients with Diabetes Mellitus (DM). Material and Methods: In this cross-sectional study, 40 eyes of 20 patients with DM alone (control group) and 70 eyes of 35 patients with heart failure and DM were included. Anterior segment and dilated fundus examination were performed in all patients. DR was classified as mild, moderate, severe non -proliferative DR and proliferative DR. According to the ejection fraction (EF), the stage of heart failure was classified as decreased (HFrEF) if LVEF <40%, moderate (HFmrEF) if LVEF was 40-49%, and preserved (HFpEF) if LVEF >= 50%. After this staging of HF patients; 13 were classified as HFpEF, 12 as HFmrEF and 10 as HFrEF Results: In our cross-sectional study, the mean age of the patients in the HF+DM+ group consisting of 35 patients was 54.4 +/- 12.6 and the mean age of the control group consisting of 20 patients was 51.7 +/- 6.8. PDR and DR in the HFrEF group were found to be significantly higher than the control (p=0.02, p=0.04 respectively. In addition, as a result of examining the relationship between the factors affecting the severity of DR, the duration of DM (p=0.01, OR=1.62), HbA1c (p=0.03, OR=2.95) and HF severity (p=0.02, OR=1.86). Discussion: Our study shows that the risk of PDR is increased in the HFrEF stage in patients with HF accompanying DM, in addition to blood glucose regulation, HF treatment may contribute positively to DR.eninfo:eu-repo/semantics/closedAccessDiabetic RetinopathyProliferative Diabetic RetinopathyHeart FailureHypoxiaArticle15429329610.4328/ACAM.22116N/A