Karahaliloğlu, ZeynepKılıçay, EbruDenkbaş, Emir Baki13.07.20192019-07-2913.07.20192019-07-2920172169-14012169-141Xhttps://doi.org/10.1080/21691401.2016.1203796https://hdl.handle.net/20.500.12451/5790Antimicrobial mixed dressings have traditionally been used to minimize bacterial infection of burns and other wounds. This study presents the advancement of biocompatible chitosan/silk sericin (CHT/SS) scaffolds combined with lauric acid (LA) and zinc oxide nanoparticles (nZnO) for the successful wound dressing applications. Antibacterial assay results showed that the diameters of the inhibition zone increased from 2 +/- 0.4 to 7 +/- 0.1mm for Escherichia coli, as well as from 2.5 +/- 0.2 to 6 +/- 0.4mm for Staphylococcus aureus while CHTS/SS/100nZnO compared to CHT/SS/0.01LA. The results not only showed excellent inhibition against Gram-positive and Gram-negative bacterial growth but also revealed improved proliferation and extended viability for HaCaT cells.eninfo:eu-repo/semantics/openAccessChitosanLauric AcidSilk SericinWound DressingZinc Oxide NanoparticlesArticle4561172118510.1080/21691401.2016.120379627396677Q1WOS:000404022000015N/A