Oberemko, AlonaSalaberria, Asier M.Saule, RitaSaulis, GintautasKaya, MuratLabidi, Jalel2019-07-042019-07-042019https://dx.doi.org/10.1016/j.carbpol.2019.05.073https://hdl.handle.net/20.500.12451/1844Kaya, Murat ( Aksaray, Yazar )Chitosan samples from two mushroom species (Boletus bovinus, Laccaria laccata) were obtained and characterized by viscosimetry, attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), elemental analyses (EA), nuclear magnetic resonance spectroscopy (13C NMR), X-ray diffraction (XRD) and thermogravimetric (TGA) analyses. Properties of the fungal chitosan samples were compared to commercial low-molecular weight chitosan, crustacean chitosan (Cervimunida johni) and chitosan obtained from an insect (Hilobius abietis). Additionally, the cytotoxic properties of chitosan in vitro on cancerous hepatoma and non-cancerous ovary cells cultivated on films with different chitosan concentrations was evaluated. As a conclusion, this study clearly revealed that low-molecular weight chitosan films and solutions with high degree of deacetylation can act cytotoxically on both tumor MH-22A and normal CHO cells in vitro. Consequently, this work may be useful for further investigations of natural anticancer products in medical areas....eninfo:eu-repo/semantics/embargoedAccessMushroomChitosanCancerLow-Molecular WeightDeacetylationArticle2211910.1016/j.carbpol.2019.05.073N/AN/A