Topçu, Aykut ArifÖzgür, Erdo?anYılmaz, FatmaBereli, NilayDenizli, Adil13.07.20192019-07-1613.07.20192019-07-1620190921-51071873-4944https://doi.org/10.1016/j.mseb.2019.04.018https://hdl.handle.net/20.500.12451/4576Molecular imprinting technique is used to design artificial creatinine receptor on the gold surface of surface plasmon resonance (SPR) chip using N-methacryloyl-(L)-histidine methyl ester (MAH), as a functional monomer. Surface characterization of SPR sensor chip is performed with atomic force microscope (AFM), ellipsometry and contact angle measurements. Creatinine imprinted SPR sensor is characterized with a linear range between 1 and 100 mM and limit of detection (LOD) and limit of quantification (LOQ) of creatinine are found 57 mu M and 190 mu M, respectively. N-hydroxysuccinimide (NHS) and creatine molecules are selected to examine the selectivity of creatinine imprinted SPR sensor. Reusability studies of SPR sensor is determined in urine mimic samples.eninfo:eu-repo/semantics/closedAccessCreatinineSurface Plasmon ResonanceMolecular ImprintingArtificial ReceptorArticle24461110.1016/j.mseb.2019.04.018Q1WOS:000471359400002N/A