Karahaliloğlu, ZeynepDemirbilek, MuratŞam, MesutSağlam, NecdetMızrak, Alpay KorayDenkbaş, Emir Baki13.07.20192019-07-2913.07.20192019-07-2920162169-14012169-141Xhttps://doi.org/10.3109/21691401.2014.913053https://hdl.handle.net/20.500.12451/6259The aim of the study is in vitro investigation of the feasibility of surface-modified bacterial nanofibrous poly [(R)-3-hydroxybutyrate] (PHB) graft for bladder reconstruction. In this study, the surface of electrospun bacterial PHB was modified with PEG- or EDA via radio frequency glow discharge method. After plasma modification, contact angle of EDA-modified PHB scaffolds decreased from 110 +/- 1.50 to 23 +/- 0.5 degree. Interestingly, less calcium oxalate stone deposition was observed on modified PHB scaffolds compared to that of non-modified group. Results of this study show that surface-modified scaffolds not only inhibited calcium oxalate growth but also enhanced the uroepithelial cell viability and proliferation.eninfo:eu-repo/semantics/openAccessBladder ReconstructionCalcium Oxalate StonesNanotexturepoly [(R)-3-hydroxybutyrate] (PHB)Tissue EngineeringArticle441748210.3109/21691401.2014.91305324863802Q1WOS:000368022400010N/A