Kemeriz, FundaTuncer, Sibel ÇiğdemAcar, Emine MügeTu?rul, Burcu2020-06-102020-06-1020201396-0296https://dx.doi.org/10.1111/dth.13393https://hdl.handle.net/20.500.12451/7573*Kemeriz, Funda( Aksaray, Yazar ) *Tuncer, Sibel Çiğdem( Aksaray, Yazar )Acne vulgaris is a multifactorial skin disorder. Many etiological factors are speculated to contribute to the pathogenesis of acne, one of these is vitamin D deficiency. Previous studies reported contradictory results about serum 25 hydroxy vitamin D (25-OH vitamin D) levels, its association with acne, some claimed that acne lesion might improve with vitamin D supplementation. We aimed to assess serum 25-OH vitamin D levels in acne patients, identify their relation with disease severity in a larger study group. The study included 134 acne patients, 129 controls. Acne disease severity was identified with Global Acne Grading Scale (GAGS) scores. Serum 25-OH vitamin D levels were measured in all groups. Serum 25-OH vitamin D levels were significantly lower in acne patients than in controls (P <.001). The prevalence of vitamin D deficiency was significantly higher in acne group than in control group (77.6% vs 63.9%; P =.041). There was a negative-strong statistically significant correlation detected between serum 25-OH vitamin D levels and GAGS scores in patient group (P <.001; r = ?.910). According to these results, we claim that evaluating serum 25-OH vitamin D levels in acne patients, vitamin D supplementation as a treatment option may be a consideration for further studies.eninfo:eu-repo/semantics/embargoedAccessAcneDisease SeverityVitamin DArticle----10.1111/dth.1339332268447Q1WOS:000530633200001Q3