Aşan Özüsağlam, MeltemGünyaktı, Ayşe2022-05-232022-05-2320220003-925Xhttps:/dx.doi.org/10.2376/0003-925X-73-58https://hdl.handle.net/20.500.12451/9412In this study, the safety evaluation, health-beneficial potential, probiotic and functional properties of Lactobacillus delbrueckii MA-9 strain originating from human breast milk were investigated in vitro. MA-9 strain showed very high resistance to simulated in vitro gastrointestinal conditions and food preservatives. The strain demonstrated non-hemolytic activity, inhibitory action on different indicator pathogen microorganisms (twelve clinical or human food-borne bacteria, two yeast and seven bacterial fish pathogens), high levels of aggregation, strong cholesterol removal ability and 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (43.40%). Moreover, the strain showed positive a-amylase and lichenase (beta-1,3-1,4-glucanase) enzyme activities. The results demonstrated that the L. delbrueckii MA-9 strain can be a good probiotic candidate and natural food additive to promote health.eninfo:eu-repo/semantics/closedAccessHuman MilkEnzyme ActivityAnti-cholesterol AbilityAggregationArticle732586610.2376/0003-925X-73-58WOS:000787559800002Q4