Kaçer, İlkerÇağlar, AhmetAkıllı, Nazire Belgin2022-02-252022-02-2520230003-1348https:/dx.doi.org/10.1177/00031348221074220https://hdl.handle.net/20.500.12451/9229Diagnosis of acute mesenteric ischemia (AMI) in its early stages is important for reversing ischemic damage. The CRP to albumin (CRP/Alb) ratio has been defined as an inflammatory indicator and is associated with the severity of inflammation and mortality rates. However, the prognostic value of CRP/Alb has not been evaluated in patients with AMI. Here, we aimed to examine the prognostic significance of CRP/Alb and compare it with other inflammatory markers. Materials and Methods: In this retrospective, case-control study, we included patients diagnosed with AMI at the emergency department between January 1, 2016, and December 31, 2020. In addition to demographic characteristics, lactate, D-dimer, white blood cell (WBC), CRP/Alb, and neutrophil/lymphocyte ratio (NLR) were recorded. Testing characteristics of CRP/Alb in predicting in-hospital mortality were studied. Results: The mean age of 132 patients was 66.48 ± 15.95 years and 71 (53.8%) of them were male. The cut-off value obtained using the receiver operating characteristic (ROC) curve for in-hospital mortality was a CRP/Alb ratio of >1.32 (sensitivity, 93.65%; specificity, 69.57%; +LR, 3.08; ?LR,.091; AUC,.782; 95% CI,.70-.85; P <.0001). The comparison of ROC curves between CRP/Alb and WBC, NLR, and lactate revealed a statistically significant difference (P <.05), whereas there was not any statistically significant difference between the ROC curves of CRP/Alb and D-dimer (P =.47). Conclusion: C-reactive protein/albumin ratio is a powerful predictor of in-hospital mortality for AMI patients. It was superior to WBC, NLR, and lactate. It could be used to determine low-risk patients and help clinicians with treatment options.eninfo:eu-repo/semantics/closedAccessAcute Mesenteric IschemiaAlbuminC-reactive ProteinD-dimerNeutrophil/lymphocyte RatioIn-hospital MortalityArticle----10.1177/00031348221074220Q3