İnci, SinanNar, GökayErol, Mustafa KemalDemirelli, SelamiDuman, HakanSerdar, SerkanErol, Fatih13.07.20192019-07-1613.07.20192019-07-1620150742-2822https://dx.doi.org/10.1111/echo.12799https://hdl.handle.net/20.500.12451/2465PubMed ID: 25345485Aim The aim of this study was to evaluate the effects of percutaneous mitral balloon valvuloplasty (PMBV) on short- and intermediate-term aortic stiffness in patients with mitral stenosis. Materials and Methods This prospective study included 56 patients with critical mitral stenosis in normal sinus rhythm (68% female; mean age: 42 ± 11 years) and 37 healthy controls. Aortic stiffness was measured using transthoracic echocardiography before PMBV, and 24-48 hours and 1 year post procedure. Results Aortic strain and distensibility were significantly higher in the patients with mitral stenosis, both after PMBV and 1 year post procedure, whereas the aortic stiffness index (ASI) was significantly lower. There was also a significant decrease in mitral mean gradient (MMG) and systolic pulmonary artery pressure (sPAP) after PMBV, based on echocardiography and catheterization. Mitral valve area (MVA) significantly increased after PMBV. There was a significant correlation between change in ?MVA and ?MMG and aortic elastic properties. There was a significantly negative correlation between the ?MVA and ?? aortic stiffness (r = -0.62, P < 0.001), and a significantly positive correlation between ?MMG and ?ASI (r = 0.60, P < 0.001). Conclusion Mitral valve stenosis was associated with impaired aortic stiffness and following PMBV, aortic stiffness decreased during both the acute period and the intermediate period. © 2014, Wiley Periodicals, Inc.eninfo:eu-repo/semantics/openAccessMitral StenosisPercutaneous InterventionTransthoracic EchocardiographyArticle32581381810.1111/echo.12799Q3