Synthesis and characterization of novel chiral (1r,2r)-1,2-bis[5-(aminomethylphospinic acid)-1,3,4-thiadiazol-2-yl]ethane-1,2-diols

Koparir, PelinKaraarslan, MuhsinÖrek, CahitKoparır, Metin13.07.20192019-07-1613.07.20192019-07-1620121042-65071563-5325https://doi.org/10.1080/10426507.2011.636412https://hdl.handle.net/20.500.12451/4498(1R,2R)-1,2-bis[5-(arylideneamino)-1,3,4-thiadiazol-2-yl]ethane-1,2-diol (2a-d) were synthesized by using appropriate aldehydes and (1R,2R)-1,2-bis(5-amino-1,3,4-thiadiazol-2-yl)ethane-1,2-diol (1) as a starting compound. Then, the phosphinic acid component (3a-d) were obtained from (2a-d) and hypophosporus acid. In addition, the structures of the novel chiral compounds (2a-d) and (3a-d) were confirmed by elemental analyses, IR, H-1-NMR, C-13-NMR, and P-31-NMR spectra. H-1 NMR and C-13 NMR spectra for 1, 2a, and 3a (Figures S1-S6) are available online in the Supplemental Materials.eninfo:eu-repo/semantics/embargoedAccess1,3,4-ThiadiazoleAminophosphinic AcidTartaric AcidEthane-1,2-diolSynthesis and characterization of novel chiral (1r,2r)-1,2-bis[5-(aminomethylphospinic acid)-1,3,4-thiadiazol-2-yl]ethane-1,2-diolsArticle187786487010.1080/10426507.2011.636412Q3WOS:000304595400008N/A