Kashani, ElmiraPesyan, Nader NorooziTunç, TuncayŞahin, Ertan13.07.20192019-07-2913.07.20192019-07-2920150009-45362192-6549https://doi.org/10.1002/jccs.201400320https://hdl.handle.net/20.500.12451/6107Reaction of 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrum's acid) with various solid aldehydes in the presence of cyanogen bromide and solid sodium ethoxide (EtONa) leads to the selective and efficient formation of bis-spiro cyclopropanes based on Meldrum's acid at the range of 0 degrees C to room temperature. The products were obtained in good to excellent yields. Structure elucidation is carried out by H-1 NMR, C-13 NMR, FT-IR spectroscopy, mass analyses and X-ray crystallography techniques. A possible mechanism for the formation of products is also discussed under solvent-free condition.eninfo:eu-repo/semantics/closedAccessMeldrum's acidAldehydeCyanogen BromideBis-spiro CyclopropanesMillingSolid Sodium EthoxideArticle62324925610.1002/jccs.201400320WOS:000351681900006N/A