• The antagonistic effects of temozolomide and trichostatin a combination on MGMT and DNA mismatch repair pathways in Glioblastoma 

  Güven, Mustafa; Taşpınar, Filiz; Denizler-Ebiri, Farika Nur; Castresana, Javier S; Taşpınar, Mehmet (Springer, 2023)

  Glioblastoma is the most aggressive and fatal form of brain cancer. Despite new advancements in treatment, the desired outcomes have not been achieved. Temozolomide (TMZ) is the first-choice treatment for the last two ...

• The protective effects of chrysin on cadmium-induced pulmonary toxicity; a multi-biomarker approach 

  Akaras, Nurhan; İleritürk, Mustafa; Gür, Cihan; Küçükler, Sefa; Öz, Mehmet; Kandemir, Fatih Mehmet (Springer Science and Business Media Deutschland GmbH, 2023)

  This study aimed to determine the potential protective effects of chrysin (CHR) on experimental cadmium (Cd)-induced lung toxicity in rats. To this end, rats were divided into five groups; Control, CHR, Cd, Cd + CHR25, Cd ...

• Protective effects of zingerone against sodium arsenite-induced lung toxicity: A multi-biomarker approach 

  Şimşek, Hasan; Küçükler, Sefa; Gür, Cihan; İleritürk, Mustafa; Aygörmez, Serpil; Kandemir, Fatih Mehmet (Mashhad University of Medical Sciences, 2023)

  Sodium arsenite (SA) exposure is toxic to the body. Zingerone (ZNG) is a flavonoid with many biological properties found naturally in honey and plants. This study aimed to determine the effects of ZNG on SA-induced rat ...

• The effect of biceps tenotomy on superior humeral migration in arthroscopic repaired full-thickness supraspinatus tears 

  Aydın, Mahmud; Çapkın, Sercan; Sürücü, Serkan; Karahasanoğlu, Rıdvan; Yılmaz, Murat (Elsevier B.V., 2023)

  Lesions of the long head of the biceps (LHB) tendon are a prevalent injury that frequently coexists with rotator cuff injuries. This study aimed to assess the effect of supraspinatus (SST) repair with concurrent LHB tenotomy ...

• Risk factors for mortality and morbidity in Syrian refugee children with penetrating abdominal firearm injuries: an 1-year experience 

  Tuşat, Mustafa; Özmen, İsmail; Demirtaş, Mehmet Semih; Ateş, Can; Öztürk, Ayşe Betül; Author profile preview; Başar, Dilek (Turkish Association of Trauma and Emergency Surgery, 2023)

  Despite improvements in technology and surgical techniques, abdominal injuries caused by firearms in children are traumatic with high complication rates and mortality. In this study, factors affecting mortality and ...

• Does glenoid bone loss accompany posterior shoulder instability with only labral tear? A magnetic resonance imaging–based study 

  Orhan, Özlem; Sezgin, Erdem Aras; Özer, Mustafa; Ataoğlu, Muhammet Baybars; Kanatlı, Ulunay (Elsevier Inc., 2023)

  The primary aim of this study was to investigate bone loss in the glenoid with magnetic resonance imaging in posterior shoulder instability with only a labral tear. Methods: A total of 76 patients operated on because of ...

• Usefulness of the four-variable formula on serial electrocardiograms in detecting subtle anterior myocardial infarction 

  Sert, Ekrem Taha; Gül, Murat; Kokulu, Kamil; Mutlu, Hüseyin (W.B. Saunders, 2023)

  To perform serial electrocardiogram (ECG) analyses in patients with subtle ECG changes in the anterior leads and evaluate the performance of the four-variable formula in detecting left anterior descending (LAD) coronary ...

• Association between thiol-disulfide hemostasis and transient tachypnea of the newborn in late-preterm and term infants 

  Demirtaş, Mehmet Semih; Erdal, Hüseyin; Kılıçbay, Fatih; Tunç, Gaffari (BioMed Central Ltd, 2023)

  Transient tachypnea of the newborn (TTN), which is the most common respiratory disease in the neonatal period, increases respiratory workload in newborns. We purposed to evaluate the oxidative stress (OS) status and thiol ...

• Vitamin D may assist the UPR against sodium fluoride-induced damage by reducing RIPK1, ATG5, BECN1, oxidative stress and increasing caspase-3 in the osteoblast MC3T3-E1 cell line 

  Yüksek, Veysel; Dede, Semiha; Çetin, Sedat; Usta, Ayşe; Taşpınar, Mehmet (Elsevier GmbH, 2023)

  Out of all measure systemic exposure to fluorides can cause defect of skeletal and dental fluorosis. Endoplasmic reticulum (ER) stress is caused by fluorine-induced oxidative stress and importance of vitamin D in its ...

• Türk Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Derneği Kanıta Dayalı Bruselloz Tanı ve Tedavi Klinik Uygulama Rehberi, 2023 

  Şimşek Yavuz, Serap; Xu, Chengcheng; Benli, Aysun; Ateş, Can; Aydın, Mehmet; Aygün, Gökhan; Azap, Alpay; Kurt Azap, Özlem (DOC Tasarım ve Bilişim TİC. LTD. ŞTİ, 2023)

  Bruselloz, dünyada ve ülkemizde çok yaygın olarak görülmesine rağmen hastalığın tanı ve tedavisini yönlendirmede kullanılabilecek kanıta dayalı bir rehber bulunmamaktadır. Bu rehber, brusellozun tanı ve tedavisi ile ilgilenen ...

• Türkiye’nin İç Anadolu Bölgesindeki İnsanlardan Kistik Ekinokokkoz Etkeni Echinococcus equinus ve Echinococcus ortleppi Türlerinin İzole Edilmesi 

  Eroğlu, Fadime; Ordu, Melike (Bilimsel Tıp Yayınevi, 2023)

  Echinococcus granulosus sensu strico’nun neden olduğu kistik ekinokokkoz (KE) hastalığı, tarımın ön planda olması, sosyo-ekonomik durumun düşük olması ve hijyenik şartlarda olmayan hayvan kesimleri nedeniyle Türkiye’de çok ...

• The Role of Matrix Metalloproteinase As Biomarkers For Neural Tube Defect 

  Akyol, Mehmet Edip; Denizler Ebiri, Farika Nur; Taşpınar, Filiz; Yüksek, Veysel; Tuncer, Oğuz; Arslan, Mehmet; Taşpınar, Mehmet (Erbil Karaman, 2023)

  Neural Tube Defect (NTD) is one of the most common congenital malformations. It is crucial to determine the prognostic, predictive, or therapeutic genetic factors for prevent ing NTD. The formation of the extracellular ...

• Sitomegalovirus, Rubella ve Toksoplasma Gondii’nin Gebelerdeki Seropozitifliği ve IgG Avidite Testleri 

  Çiçek, Cemal; Akıneden, Altan; Türkel, Selçuk (Ahi Evran Üniversitesi Tıp Fakültesi, 2023)

  Sitomegalovirus (CMV), Rubella ve Toksoplasma gondii (T.gondii) enfeksiyonları, gebe kadınlarda, özellikle ilk trimesterde ortaya çıktığında fetusta konjenital malformasyona neden olmaktadır. Bu çalışmada gebelerde CMV, ...

• Relationship Between Heart Rate Recovery and Mean Platelet Volume in Healthy Individuals 

  Aktaş, Halil; Gül, Murat; İnci, Sinan; Yıldırım, Oğuz (Ali Cangül, 2023)

  Heart rate recovery index (HRRI) and mean platelet volume (MPV) are two cardiovascular prognostic markers. Low HRRI and high MPV values have been observed in several diseases and conditions. However, the relationship between ...

• Relationship Between Chronic Obstructive Pulmonary Disease and Severity of Diabetic Retinopathy 

  Taşlıpınar Uzel, Ayşe Güzin; Yaşar, Erdoğan; Çoşkun, İbrahim Güven; Sayın, Serhat; Uzel, Mehmet Murat (Gazi Göz Vakfı, 2023)

  The negative effects of chronic obstructive pulmonary disease (COPD) on diabetes mellitus (DM) patients are known. For these reasons, we aimed to investigate the effect of COPD on the severity of diabetic retinopathy (DRP) ...

• Plasma Apelin Levels and Thiol/Disulfide Balance in Patients with Type 2 Diabetes Mellitus 

  Gezici Güneş, Ümran; Turgut, Faruk; Erdal, Hüseyin; Doğan, Serdar (Murat Demir, 2023)

  The main objective of this research is to investigate the relationship between the plasma apelin concentrations, oxidative stress biomarkers (dynamic thiol/disulfide balance), and albuminuria in patients with type 2 diabetes ...

• Is there a relationship between kinesiophobia, pain, depression, disease activity, functional status and quality of life in patients with ankylosing spondylitis? 

  Karakoyun, Ahmet; Çalık, Yalkın (İnönü Üniversitesi Tıp Fakültesi, 2023)

  To evaluate the presence of kinesiophobia and its potential effects on pain, depres sion, disease activity and quality of life in patients with ankylosing spondylitis (AS). Materials and Methods: The study included 58 AS ...

• Identification of Spore-Forming Intestinal Parasites with Pentaplex Real-Time PCR 

  Eroğlu, Fadime (Cahfer Güloğlu, 2023)

  Spore-forming intestinal parasites; Cryptosporidium spp., Cyclospora spp., Cytoisospora spp., Encephalitozoon spp., and Sarcoystis spp. are very common in immunocompromised patients, but these parasites are overlooked by ...

• Batı Ege Bölgesinde α-Talasemi Genotipleri ve α-Talasemi Genotip Frekansı 

  Barış, Savaş; Yavaş, Cüneyd; Balasar, Özgür; Gördü, Zülfükar; Doğan, Mustafa; Eröz, Recep (Düzce Üniversitesi, 2023)

  Yaygın görülen bir tek gen hastalığı olan Alfa talasemi, α-globin zincirinin kusurlu sentezi ile ortaya çıkar. Globin genlerindeki bozukluklara bağlı olarak çok geniş bir klinik spektruma yayılan bu hastalıkta çok sayıda ...

• Acacetin ameliorates acetylsalicylic acid-induced gastric ulcer in rats by interfering with oxidative stress, inflammation, and apoptosis 

  Şimşek, Hasan; Akaras, Nurhan (Ali Cangül, 2023)

  Gastric ulcer (GU) is a benign lesion in which excessive acid and pepsin activity affects the mucosal ep- ithelium and is common worldwide. Gastrointestinal disturbances come to the fore among the side effects observed in ...

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