• Evaluation of receptor relationships of some drugs used in the treatment of COVID-19 by modeling studies 

  Karaduman, Tuğçe; Karataş, Mehmet; Türkmen Özcan, Merve (Oğuz KARABAY, 2023)

  It is important to investigate the interactions of drugs used in the treatment process of COVID-19 with cellular mechanisms. In this study, the aim was to investigate the interactions of Dexamethasone, Favipiravir, and ...

• An investigation of the bactericidal and fungicidal effects of algerian propolis extracts and essential oils 

  Aşan Özüsağlam, Meltem; Tacer, Songül; Boulechfar, Safia; Zellagui, Amar (Sivas Cumhuriyet Üniversitesi, 2022)

  Natural products have been used in medicine for variety of purposes for centuries. As a natural product, propolis is gaining increasing importance today due to its antimicrobial activity against pathogenic microorganisms. ...

• N-doped carbon nanomaterials as fluorescent pH and metal ion sensors for imaging 

  Sonkaya, Ömer; Ocakçı, Şeyma; Toksoy, Alihan; Pamuk Algı, Melek; Algı, Fatih (Elsevier B.V., 2023)

  Herein we describe the facile synthesis of new N-doped carbon nanoparticles (CNPs) obtained from 1,10-phenanthroline by the solvothermal method. Characterization of CNPs were carried out with transmission electron microscope ...

• Apoptotic effect of bortezomib on pancreatic islet cells in STZ-induced diabetic rats 

  Ekin, Çiğdem; Tekin Karacaer, Neslihan; Tarhan Karaoğlan, Mehtap; Örün, İbrahim; Öztürk, Kamile (Universitas Indonesia, 2022)

  This study aimed to investigate the possible apoptotic role of bortezomib (BMZ) on pancreatic islets of streptozotocin (STZ)-induced diabetic rats.Methods: Sprague-Dawley rats were divided into groups that were administered ...

• Tip 2 diyabetik hastalarda glisemik kontrolün D vitamini, B12 vitamini ve lipid profili üzerini etkilerinin araştırılması: bir retrospektif çalışma 

  Tekin Karacaer, Neslihan; Tuncer, Sibel Çiğdem (Aksaray Üniversitesi, 2022)

  Tip 2 diyabet hızla büyüyen bir halk sağlığı sorunudur. Türkiye'de tip 2 diyabet hastalarında oral antidiyabetik kullanımının D vitamini, B12 vitamini ve lipid profili üzerine etkisi hakkında sınırlı veri bulunmaktadır. ...

• CMC-based edible coating composite films from Brewer's spent grain waste: a novel approach for the fresh strawberry package 

  Öztuna Taner, Öznur; Ekici, Lütfiye; Akyüz, Lalehan (Springer Science and Business Media Deutschland GmbH, 2022)

  This study points to the coated strawberry with new edible films originating from the components of Brewer's spent grain (BSG) obtained as a large amount of waste during brewing. The aim of this study was to measure the ...

• White pitahaya as a natural additive: potential usage in cosmetic industry 

  Aşan Özüsağlam, Meltem; Çelik, İrem (Kemerovo State University, 2023)

  The awareness of some harmful side effects of the chemicals contained in synthetic cosmetics has increased the demand for herbal-based cosmetic products today. White pitahaya fruit and peel methanol extracts were prepared ...

• Comparison of ELISA and RIA methods to quantify arginine vasopressin hormone levels in cell culture 

  Özcan Türkmen, Merve; Karaduman, Tuğçe; Mergen, Hatice (Springer Science and Business Media Deutschland GmbH, 2022)

  The radioimmunoassay (RIA) method is widely used to determine the levels of arginine vasopressin (AVP) in studies, especially in cell culture studies. However, there are many difficulties and disadvantages in performing ...

• Contribution to pharmacological valorisation of Algerian arctium minus (Hill) bernh. subsp. atlanticum (Pomel) maire; antioxidant and acetylcholinesterase inhibitory activities 

  Guettaf, Sofiane; Benmerzoug, Abdelmoumen; Chawki, Bensouici; Çakmak, Yavuz Selim; Dahamna, Saliha; Baghiani, Abderrahmane; Harzallah, Daoud (Bentham Science Publishers, 2022)

  The traditional pharmacopoeia is full of potential resources for molecules with therapeutic effects involving the inhibition of enzymes linked to some diseases. Objective: This work aimed to test in vitro neuroprotective ...

• The relationship of 50 bp deletion in the promoter region of SOD1 gene with viscosity and trace elements in chronic gastritis with Helicobacter Pylori: A case study 

  Ergün, D. Düzgün (Elsevier, 2022)

  The aim of research was to evaluate the superoxide dismutase-1 (SOD1) promoter region Insertion/Deletion (Ins/Del) gene variations in chronic gastritis patients infected with Helicobacter pylori (H. pylori), as well as the ...

• Medicinal applications, chemical compositions, and biological effects of an algerian ocimum basilicum L.var genovese; with the conversion of experimental doses to humans 

  Fedoul, Firdaous Faiza; Meddah, Boumediene; Larouci, Mohammed; Touil, Aicha Tir; Merazi, Yahya; Bekhti, Nabila; Piras, Alessandra; Falconieri, Danilo; Çakmak, Yavuz Selim (Baqiyatallah University of Medical Sciences, 2022)

  This paper aims to analyze the medicinal uses of Ocimum basilicum L.var Genovese (basil) in western Algeria and its effectiveness. Materials and Methods: For the experiments, 154 structured questionnaires were collected ...

• Discovery of protein-based natural hydrogel from the girdle of the 'sea cockroach' Chiton articulatus (Chitonida: Chitonidae) 

  Çakmak, Emel; Koç-Bilican, Behlül; Avila-Poveda, Omar Hernando; Karaduman, Tuğçe; Cansaran-Duman, Demet; Williams, Suzanne T.; Kaya, Murat (PeerJ, 2022)

  Hydrogels are widely used materials in biomedical, pharmaceutical, cosmetic, and agricultural fields. However, these hydrogels are usually formed synthetically via a long and complicated process involving crosslinking ...

• Macroporous surgical mesh from a natural cocoon composite 

  Chen, Yong-Ming; Zang, Lian-Sheng; Koç-Bilican, Behlül; Bilican, İsmail; Holland, Chris; Cansaran-Duman, Demet; Karaduman, Tuğçe; Çolak, Arzu (American Chemical Society, 2022)

  Recently, traditional polymer-based surgical meshes have drawn unwanted attention as a result of host tissue complications arising from infection, biocompatibility, and mechanical compatibility. Seeking an alternative ...

• Chemical chaperone effects on arginine-vasopressin receptor 2 mutants 

  Erdem Tunçdemir, Beril; Karaduman, Tuğçe; Özcan Türkmen, Merve; Şahin, Dilara; Mergen, Hatice; Sağlar Özer, Emel (Hacettepe University, 2022)

  Improper folding of the mutant proteins may finally cause several conformational diseases such as Nephrogenic Diabetes Insipidus (NDI). In recent years, as a therapeutic strategy, chaperone treatment for such diseases is ...

• Investigation of a new Lactobacillus delbrueckii strain from human milk as a probiotic candidate 

  Aşan Özüsağlam, Meltem; Günyaktı, Ayşe (M. & H. Schaper GmbH, 2022)

  In this study, the safety evaluation, health-beneficial potential, probiotic and functional properties of Lactobacillus delbrueckii MA-9 strain originating from human breast milk were investigated in vitro. MA-9 strain ...

• In vitro and in silico evaluation of thymoquinone as potential anticancer agent in human acute myeloid leukemia hl-60 cells 

  Tekin Karacaer, Neslihan (Trakya University, 2022)

  This study aims to explore the cytotoxic, apoptotic and autophagic effects of thymoquinone on human acute myeloid leukemia. The cytotoxic effects of thymoquinone were determined with 3-(4, 5-dimethylthiazol-2-yl)-2 and ...

• Antibacterial, antioxidant, and angiotensin-I converting enzyme inhibition effects of margotia gummifera extracts rich in phenolic compounds 

  Bouchekrit, Moufida; Laouer, Hocine; Çakmak, Yavuz Selim; Hajji, Mohamed; Boutellaa, Saber; Nasri, Moncef; Akkal, Salah (2022)

  Aromatic and medicinal plants have been used to substitute synthetic drugs with natural bioactive products. Objective: The current investigation was conducted to evaluate phenol and flavonoid contents, antibacterial, ...

• 15-15-15 gübresinin kitosan ile kaplanması ve elde edilen toz malzemelerin karakterizasyonu 

  Ayık, Bektaş; Çakmak, Yavuz Selim; Kaya, Murat (Aksaray Üniversitesi, 2021)

  Gübrelerin polimerler ile kaplanarak daha yavaş ve uzun süre salınımı hem ekonomik hem de çevre kirliliğinin önüne geçilmesi açısından son derece önemlidir. Atık kerevit kabuklarından üretilen kitosanın biyolojik orijinli ...

• Characterization of chitosan-Based films with different aniseed oil content 

  Akyüz Yılmaz, Bahar; Akyüz, Lalehan; Çakmak, Yavuz Selim; Karaman Erkul, Seher; Sargın, İdris; Koç, Behlül (Sivas Cumhuriyet Üniversites, 2018)

  This paper reports the findings of a study describing the production of chitosan-based edible films incorporated with different amount of Pimpinella anisum seed oil. The chitosan-aniseed oil (CAO) composite films (CS, ...

• Evaluation of relationship between SOD1 50-bp deletion gene polymorphism, Cu, Zn Level, and viscosity in postmenopausal osteoporosis patients with vertebral fractures 

  Soyocak, Ahu; Doğaner, Fulya; Ergün, Dilek Düzgün; Budak, Metin; Coşan, Didem Turgut; Özgen, Merih (Humana Press, 2023)

  Oxidative stress plays a role in the pathogenesis of bone loss, causing low bone mineral density (BMD) and associated osteoporotic fractures. In our study, we aimed to investigate the relationship of SOD1 50-bp insertion( ...

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