Aksaray Üniversitesi Kurumsal Akademik Arşivi
DSpace@Aksaray, Aksaray Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Correction to: the effect of biopsychosocial-spiritual factors on medication adherence in chronic diseases in Türkiye (Journal of Religion and Health, (2025), 10.1007/s10943-025-02317-3)
(Kluwer Academic/Human Sciences Press Inc., 2025) Bilgin, Aylin; Döner, Ayser; Erdoğan Yüce, Gülyeter; Muz, Gamze
Correction to: Journal of Religion and Healthhttps://doi.org/10.1007/s10943-025-02317-3. In this article, the title was incorrectly given as ‘The Effect of Biopsychosocial-Spiritual Factors on Medication Adherence in Chronic Diseases in Turkey Using Structural Equation Modeling’ but should have been ‘The Effect of Biopsychosocial-Spiritual Factors on Medication Adherence in Chronic Diseases in Türkiye’.
Polysaccharide-based edible and biodegradable films from Eruca vesicaria mucilage: structural characterization, biocompatibility, and environmental impact
(Springer Science + Business Media, 2025) Koç Bilican, Behlül
This study reports the development and characterization of edible, biodegradable films based on Eruca vesicaria seed mucilage, enriched with leaf extract and seed oil. Structural, thermal, mechanical, and surface properties were analyzed using fourier transformed infrared spectroscopy, termogravimetric analysis, scanning electron microscopy, and water contact angle measurements. Functional performance was evaluated through mechanical testing, water vapor permeability, and biodegradability in soil and water. Antioxidant activity and biocompatibility were assessed via DPPH assay and cytotoxicity tests on L929 fibroblast cells. The incorporation of Eruca vesicaria extract and oil enhanced mechanical strength, thermal stability, and antioxidant capacity. EM-Oil films showed increased hydrophobicity and biocompatibility, indicating potential for food packaging and biomedical applications. In contrast, EM-Extract films exhibited high antioxidant activity (73.31%) and flexibility but adversely affected long-term cell viability. Biodegradation studies revealed significant degradation in soil within 30 days (25–45% weight loss). Overall, Eruca vesicaria-based films offer a sustainable and eco-friendly alternative to synthetic plastics. These findings support their potential use in active packaging, while future research should address formulation refinement and industrial-scale production.
Does Zn-Mediated regulation of the Kynurenine Pathway provide the link between periodontal disease and diabetes
(Springer, 2025) Afşar, Ebru; Doğan, Kadirhan; Arslan, Erdem; Eranil, Işıl; Oral, Neşe; Kuzzu, Kadir Bahadır; Ceylan, Tayfun; Öz, Mehmet
It has long been known that there is a relationship between periodontal diseases and diabetes. The present study aimed to assess the effect of pancreatic zinc (Zn) levels on Kynurenin pathways (KP) and glucose homeostasis and the impact of Thymoquinone (TQ) in the periodontal disease animal model. Ten microliters of Porphyromonas gingivalis-lipopolysaccharide (P. gingivalis-Lps) (1 mg/ml) was injected at 48-h intervals into the palatal gingiva of rats, and TQ was given by oral gavage (10 mg/kg per day) for 2 weeks. Glucose homeostasis was assessed using the Homeostatic Model Assessment (HOMA-IR), and β-cell function (HOMA-β Levels). Kynurenine (KYN), Tryptophan (TRP), kynurenic acid (KYNA), quinolinic acid (QA), KYN 3-monooxygenase (KMO), kynureninase, interferon-γ (IFN-γ), insulin, ZIP10, and caspase-3 levels measured by the enzyme-linked immunosorbent assay (ELISA). Zinc levels in the pancreas tissue and plasma samples were measured using a colorimetric method. Morphological changes in the pancreas were identified by hematoxylin and eosin staining, and X-ray radiography determined bone resorption in the maxillary bone. In the LPS group, pancreas ZIP10 and Zn levels increased, the KP pathway was altered to favor KYNA, and impaired glucose homeostasis was observed. TQ administration decreased pancreatic Zn levels, changed KP to favor QA, and improved morphological changes in the pancreas. During the progression of periodontal diseases, KP may be altered by Zn levels through ZIP10 in the pancreas, thereby impairing pancreatic function. Regulation of Zn levels may be key to shared pathways between periodontal diseases and diabetes.
The role of reit dividend policy on ex-ante portfolio allocation
(Mendel University in Brno, 2025) İlbasmış, Metin
To test the diversification benefits of REIT sub-groups formed based on dividend payout ratios, we forecast ex-ante variance-covariance matrices using a rolling window correlation and a DCC model. Regression-based mean-variance spanning tests, mean-variance efficient frontiers, and a minimum variance portfolio allocation approach using ex-ante optimization frameworks are considered. A major finding of the current study is the dividend payout ratios of REITs affect REIT market diversification benefits. Apart from extending stock market index investors’ investment universe and providing more efficient (higher profitability and/or lower risk) portfolios, REITs offer diversification benefits directly related to dividend policies. A unique level of diversification is attained by classifying REITs based on their dividend payout ratios. As well, these REIT subgroups are capable of left-shifting the efficient frontier of a market portfolio with either of the REIT sub-groups.
Preparing children for the future with environmental education
(IGI Global, 2025) Yıldırım, Bedia
The natural environment, which has been damaged by human interventions, was initially able to tolerate human-induced negative impacts, but over time this destruction has reached the dimension of environmental disaster. Although steps were taken to address environmental problems from time to time, the measures taken were not sufficient and environmental problems continued to increase. Considering that the easiest, permanent and economical way to solve problems is through education, education should be given importance in the fight against environmental problems. The prerequisite for a livable environment is to raise an environmentally sensitive generation. The first target should therefore be the critically important early childhood period. In order to invest in our future, it is necessary to increase children's contact with nature, to ensure that they love and protect nature, and to develop their attitudes and skills to contribute to nature. So what are the duties of families and educators in this regard, what can we do for a more ecological, sustainable and livable environment?.
