Aksaray Üniversitesi Kurumsal Akademik Arşivi
DSpace@Aksaray, Aksaray Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
The evaluation of the intellectual disabled children’s fundamental motor skill proficiency
(Eurasian Society of Educational Research, 2021) Ergin, Murat; Özbek, Sıtkı
The aim of this cross-sectional study is to determine the fundamental motor skills (FMS) proficiency of children with mild intellectual disabled (MID) and to compare their FMS proficiencies in terms of age and gender. This study has three purposes. These are a) Defining the FMS proficiencies of the participants, b) Examining the FMS proficiencies of the participants in terms of gender variable, c) Examining the FMS proficiencies of the participants in terms of the age variable. Participants consisted of 122 MID students aged 7-10 years (M = 8.25, SD = 0.92). FMS proficiency was evaluated with the Gross Motor Development Test-Second Edition (TGMD-2). Independent Samples t test and ANOVA test were used to test the differences between groups. As a result: a) It was observed that the participants could not perform the FMS at the mastery level. Participants failed to demonstrate FMS proficiency appropriate for their age and showed delays in FMS compared to the TGMD-2 normative sample. Most of the participants performed “below average” and “poor” for Locomotor and Object Control skills. It was determined that the participants obtained higher scores in Locomotor subtest compared to Object Control subtest, b) It was determined that boys were more FMS proficiency and subtests than girls, c) No difference was found in FMS proficiency in terms of age. These results show that opportunities need to be increased to develop the FMS proficiency.
Demographic, clinical characteristics and medications of rehospitalized patients for acute coronary syndrome: boomerang study
(Wolters Kluwer Medknow Publications, 2021) Kemaloǧlu Öz, Tuǧba; Kıvrak, Tarık; Almaghraby, Abdallah; Abdelnabi, Mahmoud; Taşar, Onur; Uygur, Begüm; Aksakal, Emrah; Paul, Gobinda; Sadri, Seyyad; Nikroo, Fatemeh; İnci, Sinan
Background: Rehospitalizations with acute coronary syndromes (ACSs) have declined over the last years, but there is a remaining need for potential further reduction of rehospitalization after ACS to determine the most predominant predictors that can guide strategies to reduce re-hospitalizations burden. Aim: This multi-center study aimed to evaluate the demographic, clinical characteristics, and medications of rehospitalized patients who suffered a new cardiac event in 12 months after admission due to ACS. Material and Methods: Patients age >18 years who have been hospitalized between November 1 2017, and April 1 2018, for ACS within12 months before the readmission for a new acute coronary event were enrolled. Results: The present study included a total of 628 (65.9% from Turkey) consecutive patients rehospitalized with ACS (ST-elevation myocardial infarction [STEMI], 23.0%; ACS without ST-elevation [NSTE-ACS], 76.9%) from 15 different countries. The majority of the rehospitalized patients were men (67.9%), and the mean age was 63.1 ± 12.53 years. 406 (64.6%) had typical, 209 (33.2%) of patients had atypical chest pain and 13 (2.07%) had not any chest pain complaint during readmission. 304 (48.41%) of patients were discharged from hospital earlier than 3 days and 107 (17.04%) of patients stayed more than 7 days. The subcategories of first index diagnosis were 227 (36.1%) STEMI; 401 (63.8%) NSTE-ACS. The mean time from index discharge to rehospitalization was 189.25 ± 118 days. 248 (39.4%) patients were re-hospitalized more than once after index discharge. The most common risk factors were diabetes mellitus (471, 75.0%). 175 (27.87%) of patients stopped taking medication before re-hospitalization. Most of the patients (69.4%) had multivessel disease. Conclusion: Several factors identify patients at higher risk of rehospitalization with ACS. Understanding and preventing these causes can prevent rehospitalization and improve their outcome.
Demographic, clinical, and Angiographic characteristics of atrial fibrillation patients suffering from de Novo acute myocardial infarction: A subgroup analysis of the MINOCA-TR study population
(CardioFront LLC, 2021) Coner, Ali; Ekmekçi, Cenk; Aydın, Gökhan; Kılavuz Doğan, Yasemin; Arıcan Özlük, Özlem; Kılıç, Salih; Çelik, Yunus; İnci, Sinan
Background: Atrial fibrillation (AF) prevalence in patients with acute myocardial infarction (MI) ranges from 3% to 25%. However demographic, clinical, and angiographic characteristics of AF patients who admitted with de novo MI are unclear. The aim of this study was to investigate the prevalence of patients presenting with de novo MI with AF. Methods: The study was performed as a sub-study of the MINOCA-TR (Myocardial Infarction with Non-obstructive Coronary Arteries in Turkish Population) Registry, a multicenter, cross-sectional, observational, all-comer registry. MI patients without a known history of stable coronary artery disease and/or prior coronary revascularization were enrolled in the study. Patients were divided into AF and Non-AF groups according to presenting cardiac rhythm. Results: A total of 1793 patients were screened and 1626 were included in the study. The mean age was 61.5 (12.5) years. 70.7% of patients were men. The prevalence of AF was 3.1% (51 patients). AF patients were older [73.4 (9.4) vs. 61.0 (12.4) years, p<0.001] than non- AF patients. The proportion of women to men in the AF group was also higher than in the non-AF group (43.1% vs. 28.7%, p=0.027). Only 1 out of every 5 AF patients (10 patients, 19.6%) was using oral anticoagulants (OAC). Conclusions: AF prevalence in patients presenting with de novo MI was lower than previous studies that issued on AF prevalence in MI cohorts. The majority of AF patients did not have any knowledge of their arrhythmia and were not undergoing OAC therapy at admission, emphasizing the vital role of successful diagnostic strategies, patient education, and implementations for guideline adaptation.
Vitamin D intoxication due to misuse: 5-year experience
(Elsevier Masson s.r.l., 2021) Çağlar, A.; Tuğçe Çağlar, H.
Introduction: Vitamin D intoxication (VDI) is a well-known cause of hypercalcemia in children and leads to serious kidney, heart, and neurological problems. In the treatment of VDI, the goal is to correct hypercalcemia. Our aim was to evaluate the clinical features of patients with VDI, identify the causes of VDI in our region, and help guide precautions and treatment of VDI. Materials and methods: The medical records of patients with VDI presenting between January 2015 and December 2019 were retrospectively analyzed. Results: In total, 38 patients aged 0.3–4 years including 20 males (52.6%) were included in the study. Vomiting (65.8%), loss of appetite (47.4%), and constipation (31.6%) were the most common symptoms. The cause of intoxication was prescribed D3 vials in 23 patients, non-prescribed D3 vials in nine patients, and incorrectly produced fish oil supplement in six patients. Admission serum calcium and 25 (OH) D levels were 3.75 ± 0.5 mmol/L and 396 ± 110 ng/mL, respectively. A statistically significant correlation was found between the serum calcium levels at the time of diagnosis and the dose of vitamin D received, serum 25 (OH) D, phosphorus, and parathyroid (PTH) levels. Nephrocalcinosis was present in 15 (39.5%) patients. The mean time to achieve normocalcemia was 6.18 ± 2 days. The mean time to achieve normocalcemia in patients treated with pamidronate was 5.94 ± 0.7 days. Conclusion: Stoss therapy should not be administered for children of families with problems of adherence to treatment. It should be noted that VDI may develop as a result of improperly produced nutritional supplements. General practitioners and pediatricians must be aware of VDI risks and explain them to parents. Pamidronate is effective for treating VDI in children.
Risk of hypercalcemia in elderly patients with hypervitaminosis D and intoxication
(Acta Endocrinologica Foundation, 2021) Batman, Adnan; Altuntaş, Y.
Objective. We aimed to determine the risk of hypercalcemia in a geriatric population with very high dose levels of 25-hydroxy-vitamin D (25(OH)D). Patients and Method. This study was designed as a retrospective, cross-sectional two-center study for examining the elderly patients with very high 25(OH)D levels (>88ng/mL) between January 2014 and December 2019. After recruitment, subgroup analyses of the patients were performed based on their calcium and vitamin D levels. Results. A total of 81.101 elderly patients, who had been evaluated for their vitamin D levels, were screened. Of the 458 (0.6%) elderly patients with 25(OH)D>88 ng/ mL according to our criteria, 217 patients with complete data were accepted into our study. The median 25(OH)D level was 103.7ng/mL (min-max:88.2-275.9). Most of the elderly patients (86.6%) with very high 25(OH)D levels were normocalcemic. When patients with hypercalcemia were compared with normocalcemic group, no difference was observed in the levels of 25(OH)D, intact parathormone (iPTH), phosphorus, alkaline phosphatase (ALP), and their age. However, the PTH suppression rate was significantly higher in hypercalcemic group (p=0.005). Conclusion. The elderly patients with very high 25(OH)D levels would appear to be mostly normocalcemic whereas life-threatening hypercalcemia would also occur. Treatment and follow-up planning should be done according to the clinical guideline recommendations.
